摘要 |
3-Phosphonate carbapenems of the Formula: <IMAGE> wherein R1 is hydrogen, alkyl, amino, -NHCO-alkyl, hydroxy, alkoxy, halo, hydroxyalkyl, carboxyl or trifluoromethyl; R2 is alkyl, substituted alkyl, heterocyclic or substituted heterocyclic; R3 is hydrogen, alkyl or substituted alkyl; and M is a metal cation of H+ are disclosed. The compounds are useful as antibiotics.
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