发明名称 3-Phosphonate carbapenems
摘要 3-Phosphonate carbapenems of the Formula: <IMAGE> wherein R1 is hydrogen, alkyl, amino, -NHCO-alkyl, hydroxy, alkoxy, halo, hydroxyalkyl, carboxyl or trifluoromethyl; R2 is alkyl, substituted alkyl, heterocyclic or substituted heterocyclic; R3 is hydrogen, alkyl or substituted alkyl; and M is a metal cation of H+ are disclosed. The compounds are useful as antibiotics.
申请公布号 US4565808(A) 申请公布日期 1986.01.21
申请号 US19830529194 申请日期 1983.09.06
申请人 MERCK & CO., INC. 发明人 ANDRUS, W. ALEXANDER;CHRISTENSEN, BURTON G.;HECK, JAMES V.
分类号 C07F9/6561;(IPC1-7):A61K31/675 主分类号 C07F9/6561
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