ALPHA-(3-TERTIARY BUTYL-5-(1,1-DIMETHYL-2-HYDROXYETHYL)-4-HYDROXYBENZYLIDENE)-GAMMA-BUTYROLACTONE, ITS PREPARATION AND ANTI-INFLAMMATORY AGENT AND BLOOD PLATELET AGGLUTINATION INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT

摘要

NEW MATERIAL:alpha-[3-t-Butyl-5-( 1,1-dimethyl-2-hydroxyethyl)-4-hydroxybenzylidene]-gamma- butyrolactone expressed by formula I and salts thereof with any substance capable of forming the salts. USE:Anti-inflammatory agents and blood platelet agglutination inhibitors. PREPARATION:The t-butyl group of alpha-[3,5-di-t-butyl-4-hydroxybenzylidene]-gamma- butyrolactone is hydroxylated by using a microorganism belonging to the genus Mucor or Aspergillus to obtain the compound expressed by formula I.