GALENICAL RETARD PHARMACEUTICAL

摘要

A solid dispersion of a pharmacologically active agent in a crystalline matrix as a carrier is characterized by an agent which a. has a solubility of maximally 0.01% at 37 DEG C in water, b. is present in the matrix at a total concentration of more than 5 percent of weight, c. is present in the matrix at a concentration of above 5 percent by weight in a coherent crystalline form. The matrix can be a polyalkylene glycol and the active agent may be a dihydropyridine etc.