摘要 |
10-Aryl-1,8-dihydroxyanthrones of formula: <IMAGE> in which Ar is: <IMAGE> R1, R2, R3, R4 and R5 are each H, halogen, -CF3, -OH, lower alkyl, lower cycloalkyl, lower hydroxyalkyl, lower alkoxy, -C IDENTICAL N <IMAGE> r' and r'' are each H or lower alkyl, n is 0 or 1 to 3 inclusive, and R' and R'' are each H, lower alkyl or aryl at least one or R1 to R5 being other than H, <IMAGE> R6 having the same significance as for R1 to R5, or (iv> <IMAGE> and their esters are useful as anti-proliferative, anti-inflammatory, anti-acne, anti-dandruff and anti-seborrhoeic agents, and act against hair loss. |