发明名称 |
Rhodamine derivatives as fluorogenic substrates for proteinases |
摘要 |
The present invention relates to a new class of novel Rhodamine derivatives. These derivatives which are bisamide substitution products are nonfluorescent. Whereas the monoamide substitution products exhibit high fluorescence. Cleavage of a single specified amide bond by bond-specific proteinases will therefore convert the nonfluorescent bisamide derivative into a highly fluorescent monoamide derivative.
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申请公布号 |
US4557862(A) |
申请公布日期 |
1985.12.10 |
申请号 |
US19830546718 |
申请日期 |
1983.10.28 |
申请人 |
UNIVERSITY PATENTS, INC. |
发明人 |
MANGEL, WALTER F.;LEYTUS, STEPHEN;MELHADO, L. LEE |
分类号 |
C07D493/10;C07K5/065;C07K5/078;C07K5/083;C09B11/24;(IPC1-7):C07D493/10 |
主分类号 |
C07D493/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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