发明名称 CYCLOPROPANE DERIVATIVE
摘要 NEW MATERIAL:1-Amino-2-guanidinomethylcyclopropane-1-carboxylic acid expressed by the formula. USE:Useful as medicines such as immunological enhancer, carcinostatic agent and anti-inflammatory agent or intermediates therefor having an immunity stimulating activity. PREPARATION:A basic amino acid-containing fraction is separated from an extract of Grate loupia carnosa with water (which may contain a hydrophilic medium such as an alcohol aqueous solution), for example, optionally followed by using the well-known separating and purifying method, to obtain an isolated aimed compound expressed by the formula. The above-mentioned compound may be synthesized by thiol-eliminating reaction of the corresponding gamma-alkylthioamino acid or by ring-enlarging reaction of a substituted olefinecarboxylic acid.
申请公布号 JPS60246360(A) 申请公布日期 1985.12.06
申请号 JP19840102281 申请日期 1984.05.21
申请人 AJINOMOTO KK 发明人 SHIBA TETSUO;WAKAMIYA TATEAKI
分类号 A61K31/195;A61P29/00;A61P35/00;A61P37/04;C07C67/00;C07C239/00;C07C279/14 主分类号 A61K31/195
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