| 摘要 |
<p>Pyridinium compounds containing a cation having the formula Ia or Ib …<CHEM>… and a pharmaceutically acceptable cation are useful as pharmaceuticals, particularly as anti-fungal agents. In formulae Ia and Ib R1 is alkyl of at least 3 carbon atoms or aralkyl; R2 and R5 are hydrogen or various defined substituents; R3 and R4 are hydrogen or lower alkyl R6 and R7 are lower alkyl or aryl(lower)alkyl or R6 and R7 represent a group having formula II… -(CH2)2-A-(CH2)2- (II)… (where A is -(CH2)n-, O,S or NR8 where n is 0, 1 or 2 and R8 is lower alkyl) or a mono- or di- (lower alkyl) substitution product of a group having formula II.</p> |
