发明名称 METHOD OF OPTICAL RESOLUTION OF ALPHA-METHYLBENZYL ALCOHOL
摘要 PURPOSE:To develop inexpensive and efficient preparation of the titled substance, having a wide application range, by hydroluzing an alpha-methylbenzyl alcohol fatty acid ester by the use of ground liver of mammal or bird. CONSTITUTION:An alpha-methylbenzyl alcohol fatty acid ester shown by the formula I, such as acetic ester, propionic ester, etc. is treated with ground liver of mammal or bird, and hydrolyzed in the presence of a buffer solution. After the reaction is over, the reaction product is extracted with an organic solvent, (+)- alpha-methylbenzyl alcohol shown by the formula II and an (-)-alpha-methylbenzyl alcohol fatty acid ester shown by the formula II is separated and collected by partial TLC, column chromatography, etc.
申请公布号 JPS60224494(A) 申请公布日期 1985.11.08
申请号 JP19840082612 申请日期 1984.04.24
申请人 NISSAN KAGAKU KOGYO KK 发明人 MATSUMOTO HIROO;ARAI KAZUTAKA;OBARA YOSHIO;TSUCHIYA SHIYUUJI
分类号 C12P41/00;C07C33/22;C07C69/025;C12P7/22;C12P7/62 主分类号 C12P41/00
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