发明名称 MATERIAL CONTAINING IMMOBILIZED PHYSIOLOGICALLY ACTIVE SUBSTANCE
摘要 PURPOSE:The titled material useful for closed blood vessel therapy, biopsy, etc., having high activity retention ratio, improved non-dispersibility, being processed into rapidly injectable sol state, obtained by immobilizing a physiologically active substance to a carrier consisting of a specific high polymer substance. CONSTITUTION:A physiologically active substance is immobilized to a carrier of laminae having <=5,000mu, preferably 200-1,000mu longer diameter, <=3,000mu, preferably 200-800mu shorter diameter, and <=2,000mu, preferably <=800mu thickness or fibers having <=30 denier, preferably 0.5-15 denier single fiber fineness, <=3mm., preferably <1mm. fiber length using a high polymer substance having >=50wt% water absorption ratio as a material. Gelatin, chitin, collagen, etc. is preferable used as the material. The material is processed into a rapidly injectable sol state when it is blended with a medium such as water, etc., and it can reduce side effects of the physiologically active substance and be made into aerosol while keeping its activity.
申请公布号 JPS60215623(A) 申请公布日期 1985.10.29
申请号 JP19840072222 申请日期 1984.04.10
申请人 UNITIKA KK 发明人 SAKAMOTO IZUMI;TAKAGI KUNIHIKO;UNIKI TSUKASA
分类号 C07K14/575;A61K9/00;A61K9/70;A61K31/565;A61K35/00;A61K38/00;A61K38/16;A61K38/43;A61K38/48;A61K39/00;C07K14/745;C07K14/755;C07K17/02;C12N11/02;G01N33/543;G01N33/544;G01N33/548 主分类号 C07K14/575
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