2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them.

摘要

Compounds useful for treating inflammation, swelling and associated pain, and psoriasis, represented by the formula: <CHEM> and the pharmaceutically acceptable acid addition salts thereof, wherein: a is an integer of 0-3: b is an integer of 0-2; n is an integer of 3-12; each X and each Y are independently -halo, -R<1>, -alkoxy, or -phenyl; and B is selected from: <CHEM> in which R<1> and R<2> are independently H, alkyl or cycloalkyl; R<3> is H, alkyl or -CH2CH2OH; and m is an integer of 3-8. Novel compounds are those wherein n is at least 6 if both a and b are 0.