| 发明名称 |
ANTAGONISTS OF CHEMOKINE RECEPTORS |
| 摘要 |
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists. |
| 申请公布号 |
CA2883353(A1) |
申请公布日期 |
2014.03.06 |
| 申请号 |
CA20132883353 |
申请日期 |
2013.08.27 |
| 申请人 |
CHEMOCENTRYX, INC. |
发明人 |
CHEN, XI;DRAGOLI, DEAN R.;FAN, PINGCHEN;LI, YANDONG;POWERS, JAY P.;PUNNA, SREENIVAS;TANAKA, HIROKO;ZHANG, PENGLIE |
| 分类号 |
C07D471/04;A61K31/437;A61K45/06 |
主分类号 |
C07D471/04 |
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