发明名称 Triphasic oral contraceptive
摘要 A method of contraception in which an estrogen and a progestogen are administered daily in a three phase sequence for 21 days is disclosed. In the first phase a combination of an estrogen and a progestogen in a low but contraceptively effective daily dosage corresponding in estrogenic activity to 0.02-0.05 mg of 17 alpha -ethinylestradiol and in progestogenic activity to 0.065-0.75 mg of norethindrone is administered for 5-8 days; followed by the administering of the same dosage of estrogen and a progestogen corresponding in progestogenic activity to 0.25-1.0 mg of norethindrone for 7-11 days; followed by the administering of the same dosage of estrogen and a progestogen corresponding in progestogenic activity to 0.35-2.0 mg of norethindrone for 3-7 days; followed by 6-8 days without administering either an estrogen or a progestogen.
申请公布号 US4544554(A) 申请公布日期 1985.10.01
申请号 US19840607038 申请日期 1984.05.04
申请人 ORTHO PHARMACEUTICAL CORPORATION 发明人 PASQUALE, SAMUEL A.
分类号 A61K31/565;(IPC1-7):A61K31/56 主分类号 A61K31/565
代理机构 代理人
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