| 摘要 |
<p>The invention concerns novel anti-arrhythmic amino-alcohol derivatives, characterized by the general formula (1)
<Chemistry id="chema01" num="0001"><Image id="ia01" he="21" wi="84" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>or pharmaceutically acceptable salts thereof, wherein
<UnorderedLists id="ula01" listStyle="none"><ListItem>R<Sub>1</Sub>, R<Sub>2</Sub> and R<Sub>3</Sub> each independently represent hydrogen, alkyl having 1-6 carbon atoms, alkoxy having 1-6 carbon atoms, acyloxy having 1-6 carbon atoms, hydroxy, halogen or optionally alkyl-substituted amino;</ListItem><ListItem>R<Sub>4</Sub> represents hydrogen, hydroxy or alkyl having 1-6 carbon atoms,</ListItem><ListItem>R<Sub>5</Sub> represents hydrogen or alkyl having 1-6 carbon atoms,</ListItem><ListItem>R<Sub>e</Sub> represents hydrogen, acyl having 1-18 carbon atoms or alkyl having 1-6 carbon atoms,</ListItem><ListItem>R<Sub>7</Sub> and R<Sub>8</Sub> each independently represent hydrogen or alkyl having 1-6 carbon atoms.</ListItem><ListItem>X represents a direct bond or an oxygen atom, and</ListItem><ListItem>n and m each independently are integers having a value of 1 or 2, whereby the sum of n and m is 2 or 3.</ListItem></UnorderedLists></p> |
