Measurement of body substances.

摘要

A method of detecting the presence in a body of a non-gaseous substrate which is volatilizable through the skin, characterised in that the method comprises introducing at the surface of the skin an enzyme selected for the substrate to be detected for a sufficient time for any of said substrate present to react with said enzyme and detecting a condition of the skin as an indication of the presence of said substrate in the body. The method is particularly suitable for determining the presence of alcohol in the body utilizing alcohol oxidase or alcohol dehydrogenase as the enzyme and employing a transcutaneous electrode arrangement for detecting skin oxygen contact.