| 发明名称 |
Process for preparing iodovinyl-estradiol |
| 摘要 |
17 alpha -[(E)-2-Iodovinyl]-estra-1,3,5(10)-triene-3,17 beta -diol wherein the iodine atom is radioactive can be produced from (E)-[3-acyloxy-17 beta -hydroxyestra-1,3,5(10)-triene-17 alpha -yl]vinyl dihydroxyborane in an excellent yield by iodinating the same and hydrolyzing the resulting 3-acyloxy-17 alpha -[(E)-2-iodovinyl]-estra-1,3,5(10)-triene-17 beta -ol.
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| 申请公布号 |
US4541957(A) |
申请公布日期 |
1985.09.17 |
| 申请号 |
US19830529908 |
申请日期 |
1983.09.07 |
| 申请人 |
THE GEORGE WASHINGTON UNIVERSITY |
发明人 |
NAKATSUKA, IWAO;ECKELMAN, WILLIAM;RZESZOTARSKI, WACLAW J. |
| 分类号 |
A61K51/00;A61K51/04;C07J1/00;C07J7/00;C07J13/00;C07J51/00;(IPC1-7):A61K49/00;A61K43/00;C07J3/00 |
主分类号 |
A61K51/00 |
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