发明名称 CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS
摘要 <p>Compounds of the formula <IMAGE> I wherein R1 is hydrogen or a conventional amino-protecting group, R2 and R3 each are independently methyl or ethyl, and R4 is methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, allyl, 2-butenyl, 3-butenyl, 2-hydoxyethyl, 3-hydroxypropyl, 2-(dimethylamino)ethyl, pyridylmethyl, pyridylethyl, benzyl or phenethyl, and nontoxic pharmaceutically acceptable acid addition salts and solvates thereof, as well as processes for their preparation, are disclosed. The compounds in which R1 is hydrogen are potent antibacterial agents.</p>
申请公布号 NZ203360(A) 申请公布日期 1985.08.16
申请号 NZ19830203360 申请日期 1983.02.22
申请人 BRISTOL-MEYERS CO. 发明人 KAMACHI, H.;OKUMURA, J.;NAITO, T.
分类号 C07D501/06;A61K;A61K31/34;A61K31/45;A61K31/545;A61K31/546;A61P31/04;C07D;C07D501/00;C07D501/02;C07D501/16;C07D501/20;C07D501/24;C07D501/38;C07D501/46;(IPC1-7):C07D501/00 主分类号 C07D501/06
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