发明名称 NEUE BENZAZEPINDERIVATE, IHRE HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL.
摘要 Compounds of general formula I <IMAGE> (wherein A represents a <IMAGE> group, wherein R7 represents a C1-3 alkyl group, and B represents a methylene or carbonyl group or A represents a -CO-CO- group and B represents a methylene group; E represents an optionally substituted ethylene, n-propylene or n-butylene group; G represents an optionally substituted methylene or ethylene group; R1 and R2 represent a hydroxy, alkyl, alkoxy or phenyl-alkoxy group or one of them represents a hydrogen atom or together they represent an alkylenedioxy group; R3 and R4 represent hydrogen atoms, halogen atoms, trifluoromethyl, hydroxy, alkyl, alkoxy or cyano groups or one of them represents a nitro group or together they represent an alkylenedioxy group; R5 represents a hydrogen atom, an alkyl, hydroxy, alkoxy or optionally substituted amino group; and R6 represents a hydrogen atom, an alkyl, alkenyl, phenylalkyl or acyl group) and acid addition salts thereof show heart-rate reducing activity. <IMAGE>
申请公布号 AT14725(T) 申请公布日期 1985.08.15
申请号 AT19820103931T 申请日期 1982.05.06
申请人 DR. KARL THOMAE GMBH 发明人 REIFFEN, MANFRED, DR., DIPL.-CHEM.;HEIDER, JOACHIM, DR., DIPL.-CHEM.;HAUEL, NORBERT, DR., DIPL.-CHEM.;AUSTEL, VOLKHARD, DR., DIPL.-CHEM.;EBERLEIN, WOLFGANG, DR., DIPL.-CHEM.;KOBINGER, WALTER, PROF. DR.;LILLIE, CHRISTIAN, DR.;NOLL, KLAUS, DR., DIPL.-CHEM.;PIEPER, HELMUT, DR., DIPL.-CHEM.;KRUEGER, GERD, DR., DIPL.-CHEM.;KECK, JOHANNES, DR., DIPL.-CHEM.
分类号 C07D223/18;A61K31/55;A61P9/06;A61P9/10;C07C59/64;C07D205/04;C07D223/16;C07D233/16;C07D243/00;C07D243/02;C07D243/04;C07D405/12;C07D491/04;C07D491/056 主分类号 C07D223/18
代理机构 代理人
主权项
地址