Halide(s) of alkyl ester(s) of acyl-tri:methyl-alkyl di:amino acids

摘要

Halides of N alpha-acyl NE, NE,NE-trimethyl L-alkyl diamino acid esters of formula (I), in which R is 1-5C linear alkyl, X(-) is a halide ion and y is 6-14, are made by selective quaternisation of the terminal amino gp. of amphiphilic derivs. from condensn. of diamino acids and fatty acid, of formula (II), with an excess of methyl halide KHCO3 methanol for 18-48 h. at 15-30 deg.C. - They can be used as bactericides against Gram positive and -negative pseudomonas.