发明名称 Powdery preparation of amorphous dihydropyridine compound.
摘要 A powdery preparation of amorphous 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-methoxycarbonylpyridine-5 -carboxyli c acid 6-(5-phenyl-3-pyrazolyloxy)hexyl ester is provided. The compound has a long-lasting hypotensive effect and the bioavailability of the compound is improved in oral administration by converting the solid structure of the preparation from a crystalline form to an amorphous form.
申请公布号 EP0147171(A2) 申请公布日期 1985.07.03
申请号 EP19840308908 申请日期 1984.12.19
申请人 TOKYO TANABE COMPANY LIMITED 发明人 MASATO, KAMIBAYASHI;SHINJI, TSUCHIYA;TSUTOMU, ARAKI;SUSUMU, TSUCHIYA
分类号 A61K31/44;A61K31/4427;A61P9/12;C07D211/90;C07D401/12;(IPC1-7):C07D401/12;A61K9/14 主分类号 A61K31/44
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