发明名称 |
Powdery preparation of amorphous dihydropyridine compound. |
摘要 |
A powdery preparation of amorphous 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-methoxycarbonylpyridine-5 -carboxyli c acid 6-(5-phenyl-3-pyrazolyloxy)hexyl ester is provided. The compound has a long-lasting hypotensive effect and the bioavailability of the compound is improved in oral administration by converting the solid structure of the preparation from a crystalline form to an amorphous form.
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申请公布号 |
EP0147171(A2) |
申请公布日期 |
1985.07.03 |
申请号 |
EP19840308908 |
申请日期 |
1984.12.19 |
申请人 |
TOKYO TANABE COMPANY LIMITED |
发明人 |
MASATO, KAMIBAYASHI;SHINJI, TSUCHIYA;TSUTOMU, ARAKI;SUSUMU, TSUCHIYA |
分类号 |
A61K31/44;A61K31/4427;A61P9/12;C07D211/90;C07D401/12;(IPC1-7):C07D401/12;A61K9/14 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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