发明名称 |
Derivatized polystyrene and other polymer supports for spectroscopic studies. |
摘要 |
Molded articles formed of polystyrene or other polymers containing an aromatic moiety can be derivatized on the surface of the article by subjecting the molded article to a chemical reaction wherein the reaction media utilizes tetramethylsulfone as the reactant solvent and a suitable substituent group which is substituted on to the aromatic moiety of the polystyrene or other polymer by electrophilic substitution. By choosing the substituent group to further include a leaving group, further substitution of the primary substituent can be effected normally by nucleophilic substitution reaction. In this way, biologically important molecules can be attached to a polystyrene or other aromatic containing polymer without effecting certain properties of the molded article such as its optical or spectroscopic clarity.
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申请公布号 |
EP0145386(A2) |
申请公布日期 |
1985.06.19 |
申请号 |
EP19840308143 |
申请日期 |
1984.11.23 |
申请人 |
CITY OF HOPE NATIONAL MEDICAL CENTER |
发明人 |
CLARK, BRIAN R. |
分类号 |
C08F8/00;B01J41/14;B01J47/00;C08J7/02;C08J7/12;G01N21/75;G01N33/48;G01N33/545;(IPC1-7):C08J7/12 |
主分类号 |
C08F8/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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