发明名称 6-CHLORO- OR 6-BROMO-1,2-DIHYDRO-3H-PYRROLO(1,2-A)-PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 Novel 5-aroyl-6-chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-7-carboxylic acids represented by the formula <IMAGE> and the pharmaceutically acceptable, non-toxic esters and salts thereof, wherein Y is chloro or bromo and Ar is an optionally substituted phenyl, 2-furyl, or 2-thienyl ring or a 3-furyl, 3-thienyl, 2-pyrrolyl or 1-alkyl-2-pyrrolyl ring. These compounds are useful as anti-inflammatory, analgesic and antipyretic agents and as smooth muscle relaxants.
申请公布号 DE3169956(D1) 申请公布日期 1985.05.23
申请号 DE19813169956 申请日期 1981.06.05
申请人 SYNTEX (U.S.A.) INC. 发明人 MUCHOWSKI, JOSEPH M.
分类号 A61K31/40;A61P13/02;A61P15/00;A61P25/04;A61P29/00;C07D207/32;C07D207/337;C07D207/34;C07D487/04;(IPC1-7):C07D487/04 主分类号 A61K31/40
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