发明名称 |
REAGENT STRIP TEST FOR ANTITHROMBIN-III |
摘要 |
<p>Disclosed is a method and device for the quantitative determination of AT-III in mammalian blood plasma. The method involves contacting a plasma sample containing excess heparin with a 3 layered reagent strip comprising: i. a first upper layer of a bibulous material con taining thrombin and a buffer; ii. a second lower layer of a bibulous material containing a fluorogenic or chromogenic substrate capable of interacting with thrombin in a time related chemical manner; and iii. a bottom layer of water impermeable material. The chemical change in the strip is determined as a function of time and this change is compared with that obtained in samples containing known amounts of AT-III.</p> |
申请公布号 |
CA1187387(A) |
申请公布日期 |
1985.05.21 |
申请号 |
CA19830427912 |
申请日期 |
1983.05.11 |
申请人 |
MILES LABORATORIES, INC. |
发明人 |
SOMMER, RONALD G.;GREENQUIST, ALFRED C. |
分类号 |
G01N33/86;A61K39/385;C12Q1/56;G01N33/48;G01N33/52;G03F7/20;(IPC1-7):C12Q1/56;C12N9/99;C12Q1/38 |
主分类号 |
G01N33/86 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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