发明名称 |
RADIOACTIVE DIAGNOSTIC AGENT AND NON-RADIOACTIVE CARRIER THEREFOR |
摘要 |
<p>: The invention relates to a 99mTc-labeled radioactive diagnostic agent useful for visualization and dynamic inspection of hepatobiliary ducts and having a high stability and no significant toxicity. The diagnostic agent comprises 99mTc in the form of a pertechnetate and a non-radioactive carrier, the non-radioactive carrier comprising an N-pyridoxyl-.alpha.-amino acid of the formula: < IMG > wherein R1 and R2 are each an atom or an atomic group present in the a-amino acid residue encompassed by the dotted line and R3, R4, R5 and R6 are each a hydrogen atom, a halogen atom, a Cl-C10 alkyl group or a C1-C10 alkyl group substituted with at least one hydrophilic group or its salt, and a reducing agent for the pertechnetate.</p> |
申请公布号 |
CA1186624(A) |
申请公布日期 |
1985.05.07 |
申请号 |
CA19810390956 |
申请日期 |
1981.11.26 |
申请人 |
NIHON MEDI-PHYSICS CO., LTD. |
发明人 |
AZUMA, MAKOTO;HAZUE, MASAAKI |
分类号 |
C07B59/00;A61K51/00;A61K51/04;C07B31/00;C07C67/00;C07D213/66;(IPC1-7):A61K43/00;A61K49/00;A61K47/00 |
主分类号 |
C07B59/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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