发明名称 RADIOACTIVE DIAGNOSTIC AGENT AND NON-RADIOACTIVE CARRIER THEREFOR
摘要 <p>: The invention relates to a 99mTc-labeled radioactive diagnostic agent useful for visualization and dynamic inspection of hepatobiliary ducts and having a high stability and no significant toxicity. The diagnostic agent comprises 99mTc in the form of a pertechnetate and a non-radioactive carrier, the non-radioactive carrier comprising an N-pyridoxyl-.alpha.-amino acid of the formula: < IMG > wherein R1 and R2 are each an atom or an atomic group present in the a-amino acid residue encompassed by the dotted line and R3, R4, R5 and R6 are each a hydrogen atom, a halogen atom, a Cl-C10 alkyl group or a C1-C10 alkyl group substituted with at least one hydrophilic group or its salt, and a reducing agent for the pertechnetate.</p>
申请公布号 CA1186624(A) 申请公布日期 1985.05.07
申请号 CA19810390956 申请日期 1981.11.26
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 AZUMA, MAKOTO;HAZUE, MASAAKI
分类号 C07B59/00;A61K51/00;A61K51/04;C07B31/00;C07C67/00;C07D213/66;(IPC1-7):A61K43/00;A61K49/00;A61K47/00 主分类号 C07B59/00
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