| 摘要 |
PURPOSE:To enable a continuous performing of required operation accurately in a very handy manner by applying a magnetic force to a carrier comprising magnetic particles whose surface is made up of a sensitizable material and sensitized with an immunologically reactive substance such as antigen and antibody to move it against gravity. CONSTITUTION:A magnetic particle 1 holds and seals up a magnetite or other magnetic core 2 into a shell spherical 3 itself in such a manner that the surface of the magnetic core 2 will not expose. An antigen substance or an antibody substance is supported on the surface of the shell to sensitize, and one magnetic particle 1 thus obtained is placed into a container 10 and a sample A such as serum of a patient is injected thereinto to cause an antigen-antibody reaction. A cleaning liquid B is poured into the container 10 to clean it up and discharged, a cleaning operation which is repeated. The magnetic particle 1 is also cleaned. The magnetic particle 1 is put back into the container 10 while an antibody liquid C labelled with an enzyme is injected thereinto to make the labelled antibody bond with an antigen-antibody composite produced from the antigen- antibody reaction. Then, a substrate reaction liquid D is injected to cause an enzyme reaction. |
