发明名称 |
An antibiotic compound and its production. |
摘要 |
<p>A purified isolate of an actinomycete identified as ATCC 39366 is capable of producing the antimicrobial compound CL-1957A which also exhibits antitumor properties. The antimicrobial compound CL-1957A is produced by cultivating isolate ATCC 39366 under aerobic conditions in a culture medium containing assimilable sources of carbon and nitrogen until a substantial quantity of the CL-1957A compound is produced, and subsequently isolating the CL-1957A compound. The antibiotic compound CL-1957A and pharmaceutical compositions comprising this substance together with a pharmaceutically acceptable carrier is also disclosed, as are methods of treating microbial infections and tumors in mammals, employing these pharmaceutical compositions.</p> |
申请公布号 |
EP0139458(A2) |
申请公布日期 |
1985.05.02 |
申请号 |
EP19840306191 |
申请日期 |
1984.09.11 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
HOKANSON,GERARD CLIFFORD;SCHAUMBERG, JOHN PHILLIP;FRENCH, JAMES CLARK;TUNAC, JOSEFINO BALLESTEROS |
分类号 |
C07D309/22;C12P17/06;(IPC1-7):C07D309/32;A61K31/35 |
主分类号 |
C07D309/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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