发明名称 Verfahren zur Herstellung substituierter Nikotinsäuren
摘要 <p>Title cpds. of formula (I) (where R is a substituent, A is H, Cl, Br, CH3 or OCH3, E is H, Cl or Br, D is Cl, Br, CF3 or, when A and L are Cl, CH3, L is H or, when A is Cl and D is CH3, CL, and M is H or lower alkyl; one of A and E being H and the other being other than H) and their salts, which have anti-inflammatory and analgesic activity, are prepd. by reacting a cpd. of formula (II) with a cpd. of formula (III): (where Q and T are reactive groups capable of condensation to give a group -NX-where X is H or a benzyl or acyl substituent which is subsequently replaced by H).</p>
申请公布号 CH501624(A) 申请公布日期 1971.01.15
申请号 CH19660003663 申请日期 1966.03.10
申请人 SCHERICO LTD. 发明人 H. SHERLOCK,MARGARET;SPERBER,NATHAN
分类号 A61K31/455;A61K31/57;C07D213/80;(IPC1-7):C07D31/24 主分类号 A61K31/455
代理机构 代理人
主权项
地址