发明名称 |
PROCESS FOR OBTAINING NEW CIS-BICYCLO (3.3.0)OCTANE DERIVATIVES |
摘要 |
<p>Cis-bicyclo[3.3.0]octane derivatives corresponding to the formula <IMAGE> (I) wherein R1 is hydrogen, a lower alkyl group or a cation and wherein R2 represents a cyclohexyl or an adamantyl group. In these compounds the phenyl radical may be arranged with respect to the double bond in the EZ- or in the E-configuration and at the carbon atom bearing the group R2 the molecule may have the RS- or S-configuration. The compounds are prepared by reacting compounds of the formulae <IMAGE> wherein R1 and R2 have the same meaning as above and R6 represents hydrogen or a protecting group. Medicaments containing these compounds act as inhibitors of blood platelet aggregation and (in higher doses) as blood pressure lowering agents.</p> |
申请公布号 |
YU257882(A) |
申请公布日期 |
1985.03.20 |
申请号 |
YU19820002578 |
申请日期 |
1982.11.18 |
申请人 |
GRUENENTHAL GMBH |
发明人 |
BOEHLKE H.;LOSCHEN G.;MICHEL G. |
分类号 |
C07C65/19;A61K31/19;A61K31/215;A61K31/235;A61P7/02;A61P9/12;C07C45/59;C07C49/743;C07C51/00;C07C51/353;C07C67/00;C07C69/757;C07C69/76;C07C405/00;C07D317/72;C07F7/18;C07F9/40;(IPC1-7):C07C69/76;A61K31/315 |
主分类号 |
C07C65/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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