发明名称 PROCESS FOR THE PREPARATION OF IMIDAZO(1,2-A)PYRIDINES
摘要 The title compds. (I) [R = H, alkyl(C1-C4), trifluoromethyl, Ar, - CH2-halogen, -CH2-(SO)n-CH3(n=0,1,2), -CH2CN, -CH2-N(R1,R2) (R1,R2=H, methyl), -CH2-O-CO-R3(R3=alkyl (C1-C4), etc..; R'alkyl(C1-C4), BCN(B=linear or branched lower alkyl), B-O-CO-R, BOR, CH2N(R1,R2), etc..; X = H, methyl, Cl, Ar, phenyl etc.; T = linear or branched alkyl(C1-C3); Z = O, S, SO, SO2, NH or a single bond were prepared by the reaction of compds. (II) and (III) [Z" = leaving group, in the case that R is not hydrogen, R' is hydrogen . The compds. (I) effectively control stomach acid secretions and protect alls.
申请公布号 KR850000240(B1) 申请公布日期 1985.03.12
申请号 KR19810000150 申请日期 1981.01.20
申请人 SCHERING CORPORATION 发明人 BRISTOL, JAMES A.;PUCHALSKI, CHESTER
分类号 A61K31/435;A61P1/04;C07D213/73;C07D471/04;(IPC1-7):C07D471/04 主分类号 A61K31/435
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