发明名称 FOERFARANDE FOER FRAMSTAELLNING AV NYA FARMAKOLOGISKT AKTIVA FENYLAZACYKLOALKANER
摘要 Compounds of the formula <CHEM> wherein Z<3> is R or R<6>CO, wherein R is an alkyl group having 1-5 carbon atoms, a hydroxyalkyl, dimethylaminoalkyl or methylthioalkyl group having 2-6 carbon atoms in the alkyl part and having the heteroatom bound in a position other than 1-position, an alkenyl group having 3-5 carbon atoms other than an 1-alkenyl group, and R<6> is an alkyl or alkoxy group containing 1-4 carbon atoms or an alkenyl group with 2-4 carbon atoms, R<7> is an alkyl group with 1-5 carbon atoms, an allyl or benzyl group, and n is 1 or 2 provided that Z<3> is other than methyl and ethyl when n is 2 and R<7> is CH3 or an acid addition salt thereof. The compounds are useful as intermediates or starting materials for preparation of therapeutically useful substituted phenyl-azacycloalkanes.
申请公布号 FI67371(C) 申请公布日期 1985.03.11
申请号 FI19810004080 申请日期 1981.12.18
申请人 ASTRA LAEKEMEDEL AB 发明人 ARVIDSSON FOLKE LARS-ERIK;CARLSSON PER ARVID EMIL;HACKSELL ULI ALF;HJORTH JOHN STEPHAN MIKAEL;LINDBERG PER LENNART;NILSSON JOHN LARS GUNNAR;SANCHEZ DOMINGO;SVENSSON NILS UNO EIMER;WIKSTROEM HAOKAN VILHELM
分类号 A61K31/445;A61K31/451;A61P25/00;A61P25/18;C07D207/00;C07D207/08;C07D211/00;C07D211/12;C07D211/22;C07D211/26;C07D211/28;C07D211/30;C07D211/34;C07D213/16;C07D213/30;C07D213/55;(IPC1-7):C07D211/22 主分类号 A61K31/445
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