发明名称 |
2-(2-((5-DIMETHYLAMINOMETHYL)FURAN-2-YL-METHYL-THIO)ETHYLAMINO)-5-(6-METHYLPYRID-3-YLMETHYL)PYRIMID-4-ONE |
摘要 |
A process for the preparation of 2-[2-((5-dimethylaminomethyl)furan-2-ylmethylthio)ethylamino]-5-(6-met hylpyrid-S HY# 3-ylmethyl)pyrimid-4-one which comprises the reaction of 2-[2-(furan-2-ylmethylthio)ethylamino]-5-(6-methylpyrid-3-ylmethyl)pyr imid-4-one dihydrochloride with an organic solution of bis(dimethylamino)methane at a pH of about 1.3 to about 2.0. The product is a useful H2-antagonist. |
申请公布号 |
ZA8305172(B) |
申请公布日期 |
1985.02.27 |
申请号 |
ZA19830005172 |
申请日期 |
1983.07.15 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES LIMITED |
发明人 |
JOHN COOPER;MICHAEL ANTHONY FORTH;ALAN WILLIAM TREMPER;KATHLEEN LAURA WERT |
分类号 |
A61K31/505;A61P43/00;C07D405/14 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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