Process for the preparation of 6-amino-nicotinonitriles

摘要

6-Amino-nicotinonitriles of the formula <IMAGE> (I) can be prepared by reacting methylene-glutacononitriles of the formula <IMAGE> with nitrogen compounds of the formula R1-NH2(III) at 0 DEG to 200 DEG C. in the presence or absence of an inert solvent. The ratio of nitrogen compound to glutacononitrile is 1 to 100:1. The substituents R1 and R4 have the meanings given in the description.