发明名称 |
Process for the preparation of 2-(4-hydroxy-phenyl)-3-methylbutyric acid. |
摘要 |
An integrated process for the preparation of 2-(4-hydroxyphenyl)-3-methylbutyric acid from the corresponding 2-(4-chlorophenyl)-3-methylbutyronitrile through hydrolysis of the nitrile by strong base to the corresponding carboxylic acid followed by formation of the corresponding phenol by nucleophilic displacement of the chlorine with a strong base in the presence of copper salts, and if so desired metallic copper, is described. |
申请公布号 |
EP0130334(A1) |
申请公布日期 |
1985.01.09 |
申请号 |
EP19840105685 |
申请日期 |
1984.05.18 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
GRASSO, CHARLES PAUL |
分类号 |
C07C59/52;B01J27/00;C07B61/00;C07C51/00;C07C51/08;C07C51/367;C07C67/00 |
主分类号 |
C07C59/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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