| 摘要 |
PROBLEM TO BE SOLVED: To provide an industrially more advantageous method for producing a substituted aminoquinazolinone derivative, proceeding the reaction in a high selectivity and exhibiting a high yield. SOLUTION: This method for producing the substituted aminoquinazolinone derivative of formula (I) is characterized by reducing a substituted iminoquinazolinone derivative of formula (II) [wherein, R is H, formyl, a 1-6C alkyl, a 1-6C alkoxy 1-3C alkyl, a 1-6C alkylsulfonyl, a (substituted) phenylsulfonyl, naphthylcarbonyl or the like; R<SP>1</SP>is a (substituted) 5-6 membered heterocyclic ring having 1-3 hetero atoms selected from O, S and N, or the like; R<SP>2</SP>is H or a 1-3C alkyl; Xs are the same or different and are each≥1 substituent such as a halogen, a halo 1-6C alkyl or the like] with hydrogen in the presence of a catalyst and a halogen-containing compound or a sulfur-containing compound. COPYRIGHT: (C)2005,JPO&NCIPI
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