摘要 |
The invention relates to novel gonadoliberine derivatives of the general formula (I) <IMAGE> (I) wherein X represents an -O-R group wherein R is a benzyl group or a C1-4 alkyl group, an <IMAGE> group wherein R1 and R2 independently stand for hydrogen, a C1-5 alkyl, aryl, aryl-C1-2-alkyl, morpholino, 1-indolinyl or 1-pyrrolidinyl group, Y is a glycine amide or a C1-4-alkyl-amide group, the addition salts thereof formed with acids used in therapy and complexes thereof as well as pharmaceutical compositions containing them, furthermore to a process for the preparation of the above compounds. The reproductive processes of vertebrates can be advantageously influenced with the compounds of general formula (I). |