发明名称 METHOD FOR PREPARING DERIVATIVES OF 2, 5- DIHYDRO- 1, 2- THIAZINO- (5 B)- INDOL- 3- CARBOXAMIDE- 1, 1- DIOXIDE
摘要 Compounds of the formula <IMAGE> WHEREIN R1 is hydrogen, methyl or ethyl; R2 is methyl or ethyl; Y is hydrogen, fluorine, chlorine, bromine, methoxy, methyl, ethyl or trifluoromethyl; and Ar is 2-thiazolyl which may have one or two methyl or ethyl substituents attached thereto; 5,6-dihydro-4H-cyclopentathiazol-2-yl; 4,5,6,7-tetrahydro-2-benzothiazolyl; 2-benzothiazolyl; 3-isothiazolyl which may have a methyl substituent attached thereto; 2-pyridyl which may have a methyl or hydroxyl substituent attached thereto; 3-pyridyl; 4-pyridyl; 4-pyrimidinyl; pyrazinyl; 2-benzimidazolyl; 2-oxazolyl which may have a methyl substituent attached thereto; 2-benzoxazolyl; or phenyl which may have a fluoro, chloro, bromo, methyl, ethyl, trifluoromethyl or methoxy substituent attached thereto; and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as their salts are useful as antiphlogistics and blood platelet aggregation inhibitors.
申请公布号 BG36499(A3) 申请公布日期 1984.11.15
申请号 BG19780038411 申请日期 1978.01.17
申请人 THOMAE GMBH, DR. KARL 发明人 TRUMMLITZ,GUENTER;ENGEL,WOLFGARD;HAARMANN,WALTER;ENGELHARDT,GUNTER
分类号 A61K31/54;A61P7/02;A61P29/00;C07D209/42;C07D513/04;C07D513/14;(IPC1-7):C07D513/04 主分类号 A61K31/54
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