发明名称 DITHIETANE DERIVATIVE, ITS PREPARATION AND USE
摘要 NEW MATERIAL:A compound shown by the formula I (R<1> and R<2> are lower alkyl). EXAMPLE:2,4-Bis[bis(isopropoxycarbonyl)methylene]-1,3-dithietane. USE:A remedy for hepatic diseases. PREPARATION:A compound [e.g., disodium 2,2-bis(isopropoxycarbonyl)ethylene- 1,1-dithiolate, etc.] shown by the formula II (M is alkali metal) is reacted in the presence of a dimerizing agent such as pivaloyl chloride, etc. in an inert solvent (e.g., THF, etc.) at -20 deg.C- the boiling point of the solvent.
申请公布号 JPS59196887(A) 申请公布日期 1984.11.08
申请号 JP19830070688 申请日期 1983.04.21
申请人 NIPPON NOYAKU KK 发明人 KUDOU MASAAKI;YANAKA KUNIAKI;KONAKA SHIGEO;KATOU MINORU
分类号 C07D339/06;A61K31/385;A61P1/16;C07D339/00 主分类号 C07D339/06
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