| 摘要 |
A process for the production of alpha -keto-carboxylic acids of the general formula: <IMAGE> wherein R1 and R2 are the same or different and are hydrogen, hydrocarbyl radicals, substituted hydrocarbyl radicals or hydrocarbyloxy radicals by reacting an acyl halide of the formula: <IMAGE> wherein R1 and R2 are as defined above and X represents halogen, in a liquid solvent medium, with an alkali metal tetracarbonyl cobaltate complex of the formula: MCo(CO)4 wherein M is an alkali metal to form the corresponding acylcobaltcarbonyl complex of the formula: <IMAGE> wherein R1 and R2 are as defined above, reacting the acylcobaltcarbonyl complex thus formed with carbon monoxide and an alkali metal hydroxide or an alkaline earth metal hydroxide at elevated temperature and elevated pressure in a liquid solvent medium to form the corresponding alkali metal salt or alkaline earth metal salt of the product alpha -keto-carboxylic acid and thereafter acidifying the salt of the alpha -keto-carboxylic acid to form the product alpha -keto-carboxylic acid.
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