| 摘要 |
The title compds. I (R=H, alkyl, alkoxy, halo; m=1-3; n=1-14) were prepd. by the reaction of 2'-deoxy-3'-5'-di-O-alkylcarbonyl-5-fluorouridine(II) with benzonic halide (III). Thus, 2.0g 2'-deoxy-3', 5'-di-o-propionyl-5-uridine in 25mL diocane was reacted with 1.7g 2-methylbenzoyl chloride in 2mL triethylamine at room temp. for 15min and then at 70oC for 30min to give 1.5g 3-(20methylbgenzoyl)-2'dioxy-3', 5'0di-o-propionyl-5-fluorouridine (yield=56.4%).
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