发明名称 |
CARBOXYALKYL DIPEPTIDES,PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
Compounds of the formula <IMAGE> and the pharmaceutically acceptable salts thereof, wherein R1, R2 and R4 are independently selected from hydrogen and lower alkyl; R3 is hydrogen, lower alkyl or amino lower alkyl; A and B taken together with the carbons to which they are attached form an alkylene ring having six carbon atoms or A and B are hydrogen; and Z is <IMAGE> <IMAGE> +TR <IMAGE> are disclosed. The compounds are useful as anti-hypertensive agents. |
申请公布号 |
ZA8300362(B) |
申请公布日期 |
1984.09.26 |
申请号 |
ZA19830000362 |
申请日期 |
1983.01.19 |
申请人 |
SCHERING CORP |
发明人 |
SMITH ELIZABETH M;NEUSTADT BERNARD R;WITKOWSKI JOSEPH T;YEHASKEL ALBERT S;DOLL RONALD J;GOLD ELIJAH H |
分类号 |
C07D209/44;A61K38/00;A61K38/55;A61P9/12;C07D207/444;C07D209/46;C07D209/48;C07D215/48;C07D217/26;C07K1/113;C07K5/02;C07K5/06;C07K14/81 |
主分类号 |
C07D209/44 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|