2-(1-PIPERAZINYL)-2,4,6-CYCLOHEPTATRIEN-1-ONEDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG, ZWISCHENPRODUKTE FUER DIESE VERFAHREN UND DEREN HERSTELLUNG UND DIE DERIVATE ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN.

摘要

2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives of formula and therapeutically acceptable acid addition salts thereof exhibit dopamine-receptor stimulating activity in a mammal and are useful for treating hyperprolactinemia, galactorrhea, amenorrhea, impotence, Parkinsonism, diabetes, acromegaly, hypertension and other central nervous system disorders. In the formula R<1> is hydrogen or a specified substituent, R<2> is hydrogen or lower alkyl and R<3> is hydrogen or a specified radical. Processes for preparing the derivatives and pharmaceutical compositions containing them are also disclosed.