发明名称 |
BICYCLOOCTANE COMPOUNDS, THEIR PRODUCTION, COMPOSITIONS CONTAINING THEM AND THEIR PHARMACEUTICAL USE |
摘要 |
A bicyclooctane derivative has the formula:
<CHEM>
wherein R1 is hydrogen or C1-4alkyl, X is ethylene or vinylene, and Y1 and Y2 are independently hydrogen or a hydroxyl-protecting group. These compounds, or pharmaceutical pharmaceutically acceptable salts of such compounds in which R1 is hydrogen, are chemically stable, have platelet antiaggregation activity without undesirable pharmacologicai activity and exhibit the duration of high biological activity. They can be prepared from the corresponding 7-keto derivative or 2-aldehyde compound with a Wittig reagent and made up into pharmaceutical compositions. |
申请公布号 |
DE3165337(D1) |
申请公布日期 |
1984.09.13 |
申请号 |
DE19813165337 |
申请日期 |
1981.03.26 |
申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
SAMI, SHUNSUKE;SUGIE, AKIHIKO;ONO, KEIICHI;KAWAKAMI, HAJIME;KOJIMA, ATSUYUKI;KATSUBE, JUNKI |
分类号 |
C07C69/013;A61K31/19;A61K31/215;A61P9/00;A61P9/10;C07C45/59;C07C45/71;C07C49/743;C07C51/00;C07C59/46;C07C59/62;C07C59/66;C07C67/00;C07C405/00;C07D317/72;C07F9/40;(IPC1-7):07C59/46;07C69/753 |
主分类号 |
C07C69/013 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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