发明名称 |
AMINOCYCLOPENTANE ALKENOIC ACIDS AND ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION |
摘要 |
<p>Compounds are described of the formula (1) (and their salts and solvates) in which: X is cis or trans -CH=CH-; R1 is C1-7 alkyl terminated by -COOR3 where R3 is H, C1-6 alkyl or C7-10 aralkyl; Y is a saturated heterocyclic amino group having 5-8 ring members; and R2 is C2-4 alkanoyl, C3-6 alkenyl (optionally substituted), C1-12 alkyl, or substituted or unsubstituted phenylalkyl, biphenylalkyl or naphthylalkyl. These compounds inhibit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and anti-asthmatic agents.</p> |
申请公布号 |
CA1173830(A) |
申请公布日期 |
1984.09.04 |
申请号 |
CA19810376369 |
申请日期 |
1981.04.28 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
COLLINGTON, ERIC W.;HALLETT, PETER;WALLIS, CHRISTOPHER J.;BRADSHAW, JOHN;HAYES, NORMAN F. |
分类号 |
C07C;C07D;C07D267/10;C07D295/04;(IPC1-7):C07D267/10 |
主分类号 |
C07C |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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