发明名称 NOVEL COMPOUNDS AND HAPTEN-IMMUNOGLOBULIN CONJUGATES DERIVED FROM THEM
摘要 Compounds of formula (I) <IMAGE> (I) in which n is 1 or 2, R1 is C1-4 alkyl, C1-4 alkoxy, nitro, amino, halo or hydroxy, m is 0, 1 or 2, R2 is an immunogenic determinant and x is 1 or 2, provided that when n is 1, x is 1 or 2 and there is one diazo moiety at the 3-position or two diazo moieties at the 3- and 5-positions, with respect to the isothiocyanate group, and the hydroxy group is at the 4-position; and provided that when n is 2, x is 1 and the diazo moiety is at the 4-position and the hydroxy groups are at the 3- and 5-positions, are described. The compounds are useful in the preparation of immunoglobulin conjugates for employment in diagnostic techniques.
申请公布号 DE3164612(D1) 申请公布日期 1984.08.09
申请号 DE19813164612 申请日期 1981.12.03
申请人 LILLY INDUSTRIES LIMITED 发明人 SIMMONDS, ROBIN GEORGE
分类号 G01N33/53;A61K39/385;C07C331/28;C07F9/76;G01N33/531;(IPC1-7):C07C161/04;C09B29/34;G01N33/54 主分类号 G01N33/53
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