摘要 |
The present invention relates to new benzoyl-phenyl-piperidine derivatives selected from the group consisting of: (i) 2-piperidinobenzophenones of the general formula: <IMAGE> (I) in which: R1, R2 and R3, which are identical or different, each represent an atom of hydrogen, a hydroxy group, CF3, a halogen, a lower alkyl group or a lower alkoxy group; R4 represents an atom of hydrogen, a halogen, an NO2 group, an NR'R'' group [where R' and R'', which are identical or different, represent an atom of hydrogen, a lower alkyl group or a CO2R group (where R represents a lower alkyl group or a benzyl group)]; R5 and R6, which are identical or different, each represent an atom of hydrogen, a C1-C4-alkyl group, an OH group, a phenyl group or a benzyl group; and (ii) acid addition salts thereof. The invention also relates to the method for preparing these new derivatives and to their use in therapeutics, particularly as immunostimulant and immunoadjuvant agents. |