发明名称 |
2-Alkoxy-5-(pyridinyl)pyridines and cardiotonic use thereof |
摘要 |
2-(R1O)-3-Q-5-PY-6-R-pyridine (I) or pharmaceutically acceptable acid-addition salts thereof are useful cardiotonics, where R1 is methyl or ethyl, R is hydrogen or lower-alkyl, PY is 4(or 3)-pyridinyl or 4(or 3)-pyridinyl having one or two lower-alkyl substituents, and Q is hydrogen, chloro or COOR' where R' is lower-alkyl, or Q is cyano only when R is hydrogen. The preparation of I and their cardiotonic use are shown.
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申请公布号 |
US4463008(A) |
申请公布日期 |
1984.07.31 |
申请号 |
US19820440505 |
申请日期 |
1982.11.10 |
申请人 |
STERLING DRUG INC. |
发明人 |
LESHER, GEORGE Y.;OPALKA, JR., CHESTER J.;SINGH, BALDEV |
分类号 |
A61K31/44;A61K31/4418;A61P9/04;C07D213/64;C07D213/80;C07D213/85;(IPC1-7):A61K31/44;C07D401/04 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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