发明名称 CIS, ENDO-2-AZABICYCLO(5,3,0)DECANE-3-CARBOXYLIC ACID DERIVATIVE AND MANUFACTURE
摘要 The invention relates to derivatives of cis,endo-2-azabicyclo[5.3.0]decane-3-carboxylic acid of the formula I <IMAGE> (I) in which R denotes hydrogen, alkyl, alkenyl or aralkyl, R1 denotes hydrogen, allyl, vinyl or a side chain of an optionally protected naturally occurring alpha -aminoacid, R2 denotes hydrogen, alkyl, alkenyl or aralkyl, Y denotes hydrogen or hydroxyl, Z denotes hydrogen, or Y and Z together denote oxygen, X denotes alkyl, alkenyl, cycloalkyl, aryl which can be substituted once, twice or three times by alkyl, alkoxy, hydroxyl, halogen, nitro, amino, alkylamino, dialkylamino or methylenedioxy, or denotes indol-3-yl, and their physiologically acceptable salts, a process for their preparation, agents containing them and their use.
申请公布号 JPS59118766(A) 申请公布日期 1984.07.09
申请号 JP19830235220 申请日期 1983.12.15
申请人 HOECHST AG 发明人 HANSUIERUKU URUBATSUHA;RAINERU HENINGU;FUORUKAA TEETSU;RAINHARUTO BETSUKAA
分类号 A61K31/40;A61K31/403;A61K38/00;A61P9/12;A61P43/00;C07D209/52;C07K1/113;C07K5/02;C07K14/81 主分类号 A61K31/40
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