| 发明名称 |
Conjugate having cytotoxicity and process for the preparation thereof. |
| 摘要 |
<p>A conjugate having cytotoxicity prepared by covalently binding a polymer which has cytotoxic substances linked to its side chains and a reactive group at its terminal to an immunoglobulin, or its fragment, which is capable of selectively binding to a particular antigen possessed by cells to be killed.</p> |
| 申请公布号 |
EP0112720(A2) |
申请公布日期 |
1984.07.04 |
| 申请号 |
EP19830307810 |
申请日期 |
1983.12.21 |
| 申请人 |
TEIJIN LIMITED |
发明人 |
KATO, YOSHINORI;UMEMOTO, NAOJI;HARA, TAKESHI;TSUKADA, YUTAKA;HIRAI, HIDEMATSU |
| 分类号 |
G01N33/53;A61K39/395;A61K45/00;A61K47/48;A61P35/00;C07K1/113;C07K14/435;C07K16/00;C07K19/00;C12Q1/02;(IPC1-7):07G7/00;61K47/00;61K39/395 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
