FOERFARANDE FOER FRAMSTAELLNING AV SOM LAEKEMEDEL ANVAENDA 1,4-TIAZIN-3-KARBOXYLSYRADERIVAT

摘要

Derivatives of 1,4-thiazane-3-carboxylic acid represented by the formula I, wherein R1 and R2 are hydrogen, an alkyl radical or a phenyl nucleus substituted or not or form a cycloalkyl radical; R3 is a hydroxyl group, OR9 group, wherein R9 may have different significations; R4 is hydrogen, alkyl or CONH2, R3 and R4 forming a hydantoin cycle, R5 and R6 representing hydrogen, alkyl, phenyl substituted or not; R7 is hydrogen, alkyl, particularly dimethyl, phenyl substituted or not, and the salts of those compounds. as well as the pharmaceutical compositions containing them and the intermediaries for their preparation, having the formulas II, III, IV: .