| 发明名称 |
Isoindole derivatives, preparation, and uses. |
| 摘要 |
<p>Novel phthalimide intermediates are reduced to 5-sulfamoyl-6-halo-3-oxoisoindole compounds bearing a substituted 1-phenylalkyl-4-piperidinyl moiety as the isoindole N-substitutent. Preferred compounds such as 6-chloro-2,3-dihydro-3-oxo-2-[1-(phenylmethyl)-4-piperidinyl]-1H-isoindole-5-sulfonamide exhibit diuretic and antihypertensive properties.</p> |
| 申请公布号 |
EP0111397(A1) |
申请公布日期 |
1984.06.20 |
| 申请号 |
EP19830306911 |
申请日期 |
1983.11.11 |
| 申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
DOLAK, TERENCE M.;MARTIN, TELLIS A. |
| 分类号 |
A61K31/445;A61K31/4427;A61K31/4465;A61K31/4468;A61K31/45;A61P3/00;A61P7/10;A61P9/08;A61P9/12;C07D211/58;C07D401/04;(IPC1-7):07D401/04;61K31/445 |
主分类号 |
A61K31/445 |
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