| 摘要 |
NEW MATERIAL:A compound shown by the formula I (R is aryl or heterocyclic group; R<1> is H, or alkyl; R<2> is H, or OH-protecting group; R<3> is H, light metal atom, or carboxy-protecting group). EXAMPLE:7beta-[2-Ureido-2-( 2-thienyl )acetamido]-7alpha-methoxy-3-[1-( 2-benzyloxycarbonyloxyethyl )-5-1H-tetrazolyl]thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid diphenylmethyl ester. USE:A preventive and remedy for microbism. PROCESS:A compound shown by the formula III (X is eliminable group) is reacted with a thiol compound (reactive derivative) shown by the formula IV. |
